Science & academia

Hands making hear shape over transgender flag in background

More than 90% of trans people are more satisfied with life after transitioning, massive new study finds

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Ninety-four percent of transgender people said that they were either a little or a lot more satisfied with their lives since they transitioned, the 2022 U.S. Transgender Survey (USTS) by the National Center for Transgender Equality (NCTE) found. The study, which is the latest edition of the influential survey of transgender people, involved 92,329 transgender and nonbinary respondents answering questions about various aspects of their lives from October 19 to December 5, 2022.

Assortment of pills

Novel AI model rapidly determines if an antidepressant will work

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Amsterdam University Medical Center (UMC) and Radboud UMC researchers have developed an algorithm that, based on patient MRI scans and other data, can determine within a week if a particular antidepressant will, offering faster relief and minimizing often painful and damaging side effects. “This is important news for patients,” said Liesbeth Reneman, Professor of Neuroradiology at Amsterdam UMC. “Normally, it takes six to eight weeks before it is known whether an antidepressant will work.”

Depiction of nerve cells

Researchers discover an effective non-opioid treatment for nerve pain

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Many available pain medications aren’t effective in reducing this often-debilitating type of chronic pain. However, researchers at the University of Texas at Austin (UT Austin), in collaboration with UT Dallas and the University of Miami, may have advanced the treatment of neuropathic pain by discovering a molecule that reduces mechanical hypersensitivity in mice.

Chromosomes

Gene therapy hailed as ‘medical magic wand’ for hereditary swelling disorder

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Hereditary angioedema, or HAE, is a rare disease that affects about one in 50,000 people. It is caused by a genetic mutation that leaves patients with leaky blood vessels, causing erratic bouts of swelling. Dr. Hilary Longhurst, the principal investigator at New Zealand’s Te Toka Tumai, Auckland City hospital, said the new single-dose therapy appeared to provide a permanent cure for her patients’ “very disabling symptoms”.

Person having blood drawn

Breakthrough Alzheimer’s blood test could detect disease 15 years before symptoms emerge

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A recent trial of 786 people – conducted by Dr. Nicholas Ashton at the University of Gothenburg in Sweden and colleagues – found the new test to be as accurate at detecting the signs of Alzheimer’s as painful lumbar punctures, and better than a range of other tests currently being worked on. Experts say it could pave the way for national screening programs for people 50 and over, and that current treatments could work better with the cases picked up earlier.

Person receiving shot in the arm

Cancer vaccine with minimal side effects nearing Phase 3 clinical trials

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The vaccine- developed by Dr. Thomas Wagner of U.S.-based Orbis Health Solutions – has already been tested in hundreds of patients with advanced forms of melanoma in Phase 2 clinical trials. The most recent data showed nearly 95% of people given only the vaccine were still alive three years after starting treatment and 64% were still disease-free. Among the most advanced forms of melanoma, disease-free survival after three years for people with stage III disease was 60% in the vaccine-only group, compared to about 39% in the placebo group.

Artist's concept of a solar power satellite in place

First ever space-to-Earth solar power mission succeeds

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A landmark test of beaming solar power to Earth from a satellite has concluded successfully after a year-long mission. Led by scientists at the California Institute of Technology, the mission completed all three of its primary experiments to test key technology for such an endeavor. They included a new origami-inspired solar panel structure, different cell designs, and a microwave transmitter.

Happy family

Consumption poverty in the U.S. has fallen 27% since 1980

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Between 1980 and 2022, consumption poverty fell from 33.8% to 6.0% even though the official poverty rate indicated a drop by only 1.5 percentage points over that same period. According to researchers from the University of Notre Dame, consumption, which measures what families are able to purchase in terms of food, housing, transportation, and other goods and services, offers a better indicator of economic well-being than income, which can fluctuate for reasons unrelated to well-being.

Person receiving nasal spray

Novel nasal COVID-19 vaccine offers longer, better immunity than jabs

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Researchers at Duke-NUS Medical School in Singapore have developed an intranasal COVID-19 vaccine that enhances the immune system’s response to the virus, providing longer-lasting, greater protection than vaccine injections, even against new and emerging variants. The novel vaccine candidate could mean fewer boosters in future.

Cancer cells

New protein test can detect 18 early stage cancers, scientists say

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The team from U.S. biotech firm Novelna wrote: “At stage I (the earliest cancer stage) and at the specificity of 99%, our panels were able to identify 93% of cancers among males and 84% of cancers among females.” It believes its cheaper, less invasive multi-cancer screening test could be a ‘gamechanger.’

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