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Viruses up close

Scientists eliminate HIV in animal genome in historic first

Existing HIV treatment used antiretroviral therapy, which is not a cure for HIV and requires lifelong use. In this study, researchers used a gene editing system to remove large fragments of HIV DNA from infected cells, along with a new drug regimen called long-acting slow-effective release. This approach eliminated HIV DNA from about one-third of the mice, marking the first time that HIV had been eradicated from the genomes of living animals.

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